P-175: Herbal Regimes and OHSS

Background: Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication that occurs in the luteal phase of an induced hormonal cycle. The aim of this study is to assess the association of herbal regimes and OHSS. Materials and Methods: This is a clinical trial study. 110 married patients were referred to Dr. Rasekh clinic from Aug 2011 to Nov 2012. All patients had a vaginal ultrasound before and after the diagnosis of OHSS. Data was analyzed by SPSS 15 software. Results: The mean age was 30.7. 52.7% of cases didn&#039;t have history of infertility, but 38.9 % primary infertility and 8.3 % with secondary infertility. The Herbal regimes include; black pepper) 61%, (ginger)25.5 %, (Cinnamon) 27.3 %, (Thyme) 19.3 %, (cumin) 14.8 %, (Chamomile) 14.5 %, (dill) 14/5%, (saffron) 14%. Consumption period was from third to eighth day of menstrual cycle for 1 to 4 months. 32(37.2%) patients were normal BMI (18.5-24.09), BMI 34(39.5%) patients <18.5, BMI >24.09 in 15(17.4%) patients, BMI >30 in 5(5.8%) patients. Dosage of herbal regimes is One tablespoon (3g). 80(93.02%) individuals consumers of herbal regimes were mild OHSS, 5(5.8%) moderate OHSS,1(1.1%)severe OHSS. Conclusion: We concluded that the indiscriminate use of herbal regimens can lead to OHSS. Some of patients have been used herbal regimens in combination of chemical drugs. We hope to obtain the appropriate dosages of herbal regimes that is safe and could be replaced by synthetic drugs with high side effects.